Grignard reagents sulphonyl

A similar procedure has been used in the synthesis of chrysanthemic acid derivatives (228) starting from isopropylidenemalonate (226) and a Grignard reagent (227) containing a sulphonyl function (equation 68). S-Containing leaving groups have also... 

The reaction between sulphonyl azides and Grignard reagents also leads to stable triazenes which are similarly degraded with alkali to aryl azides (equation 125). This reaction constitutes not... 

Sulphinate salts, obtained by reaction of sulphur dioxide with either alkyllithiums or Grignard reagents, are converted into sulphonyl chlorides upon reaction with sulphuryl chloride582, as shown in equation 149. The same reaction occurs if thionyl chloride dissolved in DMF is used583. 

Several compounds have been prepared by nucleophilic substitution of chlorine in 2-chloro-l,3-dithian with Grignard reagent (RMgBr), malonic esters, and phenols.A mechanism for the de-ethoxycarbonylation of the 2-(l,3-dithianyl)malonates by sodium chloride or sodium ethoxide has been studied. 2-Chlorotetrahydrofuran reacts with nucleophiles such as 2-lithio-2-phenyl-l,3-dithian (326) by three simultaneous mechanisms i.e. substitution, proton abstraction, and electron transfer) to give the products (327)—(330) (Scheme 12)/° When a dithian (331 R = H or COiMe) was treated with a sulphonyl chloride in pyridine, ring-expansion to the 5//-l,4-dithiepin (332) occurred instead of the expected formation of a sulphonate. ... 

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