Grignard reagents alkylation

In the general context of donor/acceptor formulation, the carbonyl derivatives (especially ketones) are utilized as electron acceptors in a wide variety of reactions such as additions with Grignard reagents, alkyl metals, enolates (aldol condensation), hydroxide (Cannizzaro reaction), alkoxides (Meerwein-Pondorff-Verley reduction), thiolates, phenolates, etc. reduction to alcohols with lithium aluminum hydride, sodium borohydride, trialkyltin hydrides, etc. and cyloadditions with electron-rich olefins (Paterno-Buchi reaction), acetylenes, and dienes.46... 

One of the most common types of reactions carried out to prepare organic derivatives of the group IVA elements is that of transferring an alkyl group by means of a Grignard reagent. Alkylation of SnCl4 can be illustrated as follows ... 

By treating fluoronanotubes with strong nucleophiles such as Grignard reagents, alkyl- and aryllithium reagents, metal alkoxides, acyl peroxides, amines and diamines, the fluorine atoms can be replaced through substitution [29, 47-50]. 

Via organometallic compounds (Grignard reagent). Alkyl halides react with either Mg or Li in dry... 

Grignard reagents, alkyl magnesium halides (R - Mg - X), react with aldehydes and ketones. 

Monocyclic triazine 2-oxides are quite stable and unreactive toward reagents such as Grignard reagents, alkyl- and aryllithiums, and other organometallics. Reduction of the 2-oxides (56) with NaBH4, however, gave the tetrahydro derivatives (57) and (58) in good yields (Equation (18))... 

Alkylation of allylic Grignard reagents. Alkylation of allylic Grignard reagents in the presence of Cuf results in almost exclusive substitution at the Imposition. The reaction is very slow in the absence of Cul. ... 

The gegen ion may be inorganic or organic, and typical initiators include KNHj, n-butyl lithium, and Grignard reagents (alkyl magnesium bromides). 

---