Gray, Douglas

Mass analysis is a relatively simple technique, with the number of ions detected being directly proportional to the number of ions introduced into the mass spectrometer from the ion source. In atomic mass spectrometry the ion source produces atomic ions (rather than the molecular ions formed for qualitative organic analysis) which are proportional to the concentration of the element in the original sample. It was Gray who first recognized that the inductively coupled plasma would make an ideal ion source for atomic mass spectrometry and, in parallel with Fassel and Honk, and Douglas and French developed the ion sampling interface necessary to couple an atmospheric pressure plasma with a mass spectrometer under vacuum. 

Douglas, G. B., C. M. Gray, B. T. Hart, and R. Beckett. 1995. A strontium isotopic investigation of the origin of suspended particulate matter (SPM) in the Murray-Darling River system, Australia. Geochim. Cosmochim. Acta 59 3799-3815. 

MI, Folder lA,Witness Statement Peter George de Carle Parker, 13 December 2001 Kenneth Earl, 15 May 2000 John Leonard Newbury, 29 April 2003 Douglas Michael Gray, 17 February 2003. 

MI, Folder iA,Witness Statement Douglas Michael Gray, 17 February 2003. 

Fahrtash-Bahin F, Karinyawasam VC, Gray T, Byth K, George J, Douglas MW. Australian tertiary care outcomes of entecavir monotherapy in treatment naive patients with chronic hepatitis B. World J Gastroenterol 2013 19(5) 721-6. 

This chapter describes the instrumentation and basic analytical capabilities of ICP-AES and ICP-MS. Some illustrative examples of analyses involving rare earths as either analyte or matrix are also described. The chosen cases reflect some of the major areas of interest but are not meant to represent all the work in the literature. Complete reviews of publications in ICP-AES are provided, in even years, in the Emission Spectrometry section of the review issue of Analytical Chemistry (Keliher et al. 1986). Applications for analysis of specific sample types, e.g., waters, metals, etc., are also reviewed therein in odd years. Analytical uses of ICPs are surveyed regularly in the ICP Information Newsletter, the Journal of Analytical Atomic Spectrometry, and the Journal of Analytical Spectroscopy. ICP-AES is also described in detail in three recent books (Boumans 1987, Montaser and Golightly 1987, Thompson and Walsh 1983), and a fourth monograph deals with applications of ICP-MS (Date and Gray 1989). Numerous reviews on ICPs (Fassel 1978), ICP-AES (Barnes 1978), and ICP-MS (Douglas and Houk 1985, Houk 1986, Gray 1985, Houk and TTiompson 1988) are also available. 

Plasma source MS is now recognized as a very powerful technique for trace element analysis. Argon ICP has been well characterized as an emission source and has, to date, been the preferred plasma for MS. The early publications by Gray and Date [1-10], Houk, Svec and Fassel [11-16], and Douglas, French and Smith [17, 18], outlined the basic fundamentals and capabilities of this technique in which singly charged ions formed in an atmospheric-pressure plasma are extracted into a quadrupole mass analyzer for detection. 

---