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Granulation particles properties

The granulated particles exhibit technical properties equal to or almost equal to the materials described in section 6.3.1. [Pg.253]

Fig. 6 Influence of the granule particle size on the theophylline release properties of the tablets containing hot-melt extruded granules (n = 3). Tablets 20% extruded granules (Formula 3 25% theophylline, 2% PEG, and 73% PVAc), 79.5% Avicel PH200, and 0.5% magnesium stearate ( ) Less than 125 pm (i) 180-212 pm (a) 300 25 pm (O) 500-600 pm. (From Ref. l)... Fig. 6 Influence of the granule particle size on the theophylline release properties of the tablets containing hot-melt extruded granules (n = 3). Tablets 20% extruded granules (Formula 3 25% theophylline, 2% PEG, and 73% PVAc), 79.5% Avicel PH200, and 0.5% magnesium stearate ( ) Less than 125 pm (i) 180-212 pm (a) 300 25 pm (O) 500-600 pm. (From Ref. l)...
The composition of the sample has a dramatic influence on extraction. Solid samples can differ significantly in their physico-chemical properties, the type of compounds they contain and their degree of granulation (particle size). These factors affect sorption and retention of analytes. [Pg.240]

Martino PD. Censi R, Malaj L. et al. Influence of metronidazole particle properties on granules prepared in a high-.shear mixer-granulator. Drug Dev Ind Pharm 2(X)7 33(2) 121-31. Lantz RJ. Size reduction. In Licberman HA, Schwartz JB, eds. Pharmaceutical Dosage Forms, 2nd ed. Vol. 2. New York Marcel Dekker, Inc., 1990 107-2(X). [Pg.83]

Di Martino P. Censi R. Malaj L. Martelli S. Barthelemy C. Influence of metronidazole particle properties on granules prepared in a high-shear mixer-granulator. Drug Dev Ind Pharm 2007 33(2) I21-31. [Pg.302]

The PB is a statement of continuity for particulate systems. It includes a kinetic expression for each mechanism which changes a particle property. Consider a section of a granulator as illustrated in Fig. 21-185. The PB follows the change in the granule size distribution as granules are born, die, grow, and enter or leave the control... [Pg.2385]

W. Pletch, "Granulate Dry Particulate Solids by Compaction and Retain Key Powder Particle Properties", Chemical Engineering Progress, April (1997), 24. [Pg.14]

W. Pietsch, Granulate dry particulate solids by compaction and retain key powder particle properties. Chem. Engng. Progr. 93 (1997)4, 24-46. [Pg.541]

The fluidized bed process offers wide flexibility to adjust the particle properties according to the requirements. So it is possible to generate only slightly agglomerated granules with excellent dissolution properties, but also very spherical particles with an even particle surface and low risk of... [Pg.394]


See other pages where Granulation particles properties is mentioned: [Pg.1882]    [Pg.1903]    [Pg.401]    [Pg.181]    [Pg.447]    [Pg.292]    [Pg.193]    [Pg.194]    [Pg.240]    [Pg.71]    [Pg.103]    [Pg.104]    [Pg.304]    [Pg.190]    [Pg.1641]    [Pg.1662]    [Pg.989]    [Pg.3203]    [Pg.3663]    [Pg.298]    [Pg.57]    [Pg.2331]    [Pg.2350]    [Pg.335]    [Pg.2314]    [Pg.2333]    [Pg.1886]    [Pg.1907]    [Pg.89]    [Pg.108]    [Pg.992]    [Pg.395]    [Pg.34]    [Pg.52]    [Pg.166]    [Pg.209]    [Pg.232]    [Pg.269]    [Pg.333]   
See also in sourсe #XX -- [ Pg.298 ]




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