Granulation-fibroid tissue

From the present results, it follows that both silocane (B) and silane (A) provide reliable activation of cicatrizing of the deep non-complicated skin thermal bum. The silocane effect on the average time for primary scab fall-off, as completion of granulation-fibroid tissue development at the site of bum necrosis, was more pronounced the time required is reduced by almost 15%. Somewhat less pronounced (about 6 - 7%) was the activation of secondary scab fall-off, but it is also of practical value, taking into account the fact of non-complicated bum cicatrizing in comparison with solkoseril (a high efficiency preparation in clinical practice), but turned out to be non-effective for a non-complicated burning process in this experiment. 

Table 3. Silocane effect on some biochemical characteristics of granulation-fibroid tissue.

The results of our bio-chemical investigations of granulation-fibroid tissue activation are determined by change in the dynamics of metabolic processes in developing a wound scab. Thus, it may be concluded drat silocanes under study are able to directly influence the functional state of connective tissue cells participating in the cicatrizing process by activation of their morfdiogenetic potentials. 

Keyword silatranes, silocanes, acrylic acids, wounds, bums, granulation-fibroid tissue... 

Attention is drawn to the decrease in average mass value of the granulation-fibroid tissue formed under the influence of both silocanes. Under the effect of B a decrease in the rihonucleic acids concentration has occurred that demonstrates the rise in the rate of biosynthetic processes in the tissue. Collagen concentrations, determined via hydroxyproline, remain at nearly the same level as the control series (under A, there are even decreased), but meanwhile a considerable decrease takes place in the concentration of hydroxylysine — an amino acid that is specific for collagens and takes... 

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