Gold salts reactions with

Carbene complexes have also been prepared by transmetallation reactions. Lithiated azoles react with gold chloride compounds and after protonation or alkylation the corresponding dihydro-azol-ylidene compounds, e.g., (381) or (382), are obtained.22 9-2264 Silver salts of benz-imidazol have also been used to obtain carbene derivatives.2265 Mononuclear gold(I) carbene complexes also form when trimeric gold(I) imidazolyl reacts with ethyl chlorocarbonate or ethyl idodate.2266,2267 The treatment of gold halide complexes with 2-lithiated pyridine followed by protonation or alkylation also yields carbene complexes such as (383).2268 Some of these carbene complexes show luminescent properties.2269-2271... 

Penicillamine Gold salts A Patients who have had gold salt therapy discontinued due to a major toxic reaction may be at greater risk of serious adverse reactions with penicillamine, but not necessarily of the same type. However, this is controversial. 

It is noteworthy that both types of reactions can also be applied to prepare (carbene)gold(m) compounds A-alkyl-thiazolium salts react with HAuG14 or NaAuCl4, followed by the addition of base, to give (thiazol-2-ylidene)gold(m)... 

One Au-C bond in bis(thiazol-2-ylidene)gold cations is cleaved in the reaction with elemental iodine to give the corresponding (carbene)AuI complex and a 2-iodo-thiazolium salt, while chlorine and bromine oxidize the gold center to the gold(m) state.267... 

Drugs can cause a wide variety of other autoimmune reactions. One example is myasthenia gravis, which is characterized by muscle weakness and is mediated by antibodies against the acetylcholine receptor at the neuromuscular junction. It has been reported in association with penicillamine [66], gold salts [67], and procainamide [68]. Another form of drug-induced autoimmunity is polymyositis, which is an autoimmune disease... 

---