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Gold disodium thiomalate

Gold sodium thiomalate (actually a mixture of mono- and disodium salts of gold thiomalic acid) is very water soluble. It is available as a light-sensitive, aqueous solution of pH 5.8 to 6.5. The gold content is approximately 50%. It is administered IM, because it is not absorbed on oral administration and is highly bound (95%) to plasma proteins. [Pg.1487]

Carcinogenicity and teratogenicity of Myo-chrisine (C4H3AuNa204S), the disodium salt of gold sodium thiomalate (C4H4AuNa04S), is reported at high doses in rats and rabbits. Renal adenomas are documented in rats at... [Pg.336]

Formula Gold(l) sodium thiomalate is a mixture of monosodium- and disodium-salts of gold thiomalate the respective molecular formulas being C4H4AuNa04S (monosodium salt) and C4H3AuNa204S (disodium salt) a tetrameric structure with S— Au—S linear units. [Pg.329]

See other pages where Gold disodium thiomalate is mentioned: [Pg.328]    [Pg.328]    [Pg.381]    [Pg.381]    [Pg.526]    [Pg.373]    [Pg.339]    [Pg.526]    [Pg.710]   
See also in sourсe #XX -- [ Pg.328 ]



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