Glycosylated polymers

Monsigny, M., Midoux, P., Mayer, R. and Roche, A.C. (1999) Glycotargeting influence of the sugar moiety on both the uptake and the intracellular trafficking of nucleic acid carried by glycosylated polymers. Biosci. Rep., 19, 125-132. 

Fajac I, Thevenot G, Bedouet L, et al. (2003). Uptake of plasmid/glycosylated polymer complexes and gene transfer efficiency in differentiated airway epithelial cells. J. Gene Med. 5 38-48. 

S. G. Withers, Mechanisms of glycosyl transferases and hydrolases, Carbohydr. Polym., 44 (2001) 325-337. 

Several methods are available to access glycosyl iodides (Scheme 2.50). Anomeric hemiacetals bearing diverse protecting groups (Bn, Bz, Ac, N3, CMe2) upon treatment with a polymer-bound triphenylphosphine-iodine complex and imidazole can be converted into a-glycosyl iodides [179]. The precipitated by-products,... 

Sulfoxide donors have been employed in the glycosylation of soluble and insoluble polymer-supported glycosyl acceptors, and the area has been reviewed [86,283]. 

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