Glycosyl phosphate monomers

Activation of the glycosyl phosphate monomers 4-8 was carried out at —15 °C in dichloromethane under acidic conditions with the Lewis acid TM-SOTf. Removal of Fmoc was accomplished by treatment with excess piperidine,... 

Wada et al. have shown that the phosphoramidite method could be applicable to the synthesis of short oligo(a-i -glycosyl phosphate) derivatives (9) from a-Z)-glycosyl phosphoramidite monomer unit (8) (Scheme 3). ... 

Kusmierek, J.T., Folkman, W., and Singer, B. (1989) Synthesis of N2,3-ethenodeoxyguanosine, N2,3-ethenode-oxyguanosine 5 -phosphate, and N2,3-ethenodeoxyguanosine 5 -triphos-phate. Stability of the glycosyl bond in the monomer and in poly(dG. epsilon dG-dC). Chem. Res. Toxicol, 2,... 

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