Glycosidation, to aglycon

RICHELLE M, PRIDMORE-MERTEN S, BODENSTAB S, ENSLEN M, OFFORD E A (2002) Hydrolysis of isoflavone glycosides to aglycones by (3-glycosidase does not alter plasma and urine isoflavone pharmacokinetics. J Nutr 132, 2587-92. 

As relatively few standard compounds are available from commercial or other sources, identification of flavonol glycosides has to be achieved by alternative means, for example UV-, H- and C-NMR spectroscopy. Therefore hydrolysing all glycosides to aglycones followed by HPLC determination offers a practical method for the quantitative determination of flavonoids in tea (Hertog et al, 1993a Wang and Helliwell, 2001). 

ATCC-9807 Saponins (sapogenin glycosides) hydrolysis of glycosides to aglycones (sapogenins) K-478... 

Rekha, C. R., Vijayalakshmi, G. (2010). Bioconversion of isoflavone glycosides to aglycones, mineral bioavailability and vitamin B complex in fermented soymilk by probiotic bacteria and yeast. Journal of Applied Microbiology, 109,1198-1208. 

Anthraquinone glycosides and aglycones can be readily separated on silica layers rising moderately polar developing solvents [41 3]. The best such solvents eonsist of ethyl acetate modified to increase polarity by the addition of alcohols or water for the glycosides or changed to decrease polarity by inclusion of hydrocarbon components. 

Fig. 2.90. Electropherograms of sterile root exudate before (a) and after incubation with Mesorhizobium loti (b) and Rhizobium leguminosarum bv. trifolii (c). From their UV spectra, peaks 1-6 were identified as resorcinol, rhamnetin, catechin, quercetin glycoside, quercetin aglycone and hesperidin. Differences in the retention times of the same compounds in different samples could be due to the variations in buffer temperature or sample composition. Reprinted with permission from H. L. Steele et al. [213].

In the context of vascular disease, numerous studies have focused on the ability of phenolic compounds, as pure aglycones and as glycosides, to delay the oxidation of LDL in This work has been paralleled by studies investigating the propensity with... 

Unlike maltose, cellobiose is a /3-glycoside. (The aglycone unit is turned 180° to permit a reasonable bond angle for the glycosidic linkage.)... 

For 0-glycosides, the plant samples are boiled with HCI/H2O to hydrolyse the anthraquinone glycosides to respective aglycones, and the then the above method for free anthraquinones is carried out. 

After the hydrolysis of a polyphenol glycoside to the free aglycone, polyphenols are conjugated by methylation, sulfation, glucuronidation or a combination. However, there are exceptions to this sequence, as... 

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