Glycosidation reductive deamination

Though less common, formation of N-glycosides also occurs in plants, and direct N-glucosidation of chloramben represents a significant detoxification pathway in tolerant but not in susceptible species." " Susceptibility was associated with the conversion of chloramben to its O-glucose ester as the prominent metabolic route. Subsequently, the N-glucosyltransferase responsible for detoxification of chloramben in tolerant soybean and tomato was isolated and partially characterized." Reference has already been made to the roles of reductive deamination and... 

Pyrimidine ribonucleotides, like those of purines, may be synthesized de novo from amino acids and other small molecules (Chapter 11). Preformed pyrimidine bases and their ribonucleoside derivatives, derived from the diet of animals or found in the environment of cells, may be converted to ribonucleotides via nucleoside phosphorylases and nucleoside kinases. In some cells a more direct pyrimidine phosphoribosyltransferase pathway has also been recognized (Chapter 12). Ribonucleotides are catabolized by dephosphorylation, deamination, and cleavage of the glycosidic bond, to uracil. Uracil may be either oxidatively or reductively cleaved, depending on the organism involved, and can be converted to CO and NH (Chapter 13). 

The catabolism of pyrimidine nucleotides, like that of purine nucleotides (Chapter 10), involves dephosphorylation, deamination, and glycosidic bond cleavage. In contrast to purine catabolism, however, the pyrimidine bases are most commonly subjected to reduction rather than to oxidation. An oxidative pathway is found in some bacteria however. 

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