Glycosaminoglycans in Eye Diseases

Macular corneal dystrophy is a rare dystrophy that is characterized by abnormal deposits in the corneal stroma, keratocytes, Descemet s membrane, and [Pg.181]

Macular corneal dystrophy can be classified into three immunophenotypes, types I, lA, and II, according to the serum level of sulfated keratan sulfate and immunoreactivity of the corneal tissue. In macular corneal dystrophy type I, the keratan sulfate level is low in both the serum and corneal tissue. In macular [Pg.182]

CS/DS Macular corneal dystrophy, glaucoma, cataract, retinal detachment/proliferative vitreoretinopathy, myopia, thyroid eye disease, pseudoexfoliation syndrome HS Glaucoma, cataract, diabetic retinopathy, retinal detachment/proliferative [Pg.183]

HA Macular corneal dystrophy, glaucoma, cataract, diabetic retinopathy, retinal [Pg.183]

keratan sulfate CS/DS, chondroitin sulfate/dermatan sulfate HS, heparan sulfate HA, hyaluronan. [Pg.183]