Glycolipids Galactosyl ceramide

Galactosyl ceramide (GLjb) Gaipi Cer Major neutral glycolipid in plasma... 

Glucosylceramide is known to be the precursor of all the major classes of glycosphingolipids in mammalian tissues, while its counterpart, galactosyl-ceramide (GL-lb or cerebroside) gives rise only to a small group of glycolipids. The metabolism of galactosylceramide is discussed later. 

Tsujimoto, T. and Ito, Y. (2007) Concise syntheses of itnmuno-stimulating glycolipids, a-galactosyl ceramides. Tetrahedron Lett., 48, 5513-5516. 

Glycolipids are important constituents of the plasma membranes, of the endoplasmic reticulum, and of chloroplasts. The cerebrosides and their sulfate esters, the sulfatides, are especially abundant in myelin. In plant membranes, the predominant lipids are the galactosyl diglycerides.29 74 The previously described ether phospholipids (archaebacteria), ceramide arnino-ethylphosphonate (invertebrates), and sulfolipid (chloroplasts) are also important membrane components. 

Chagasic sera did not differentiate between glycolipids with terminal p glucosyl or p galactosyl non-reducing units. They however discriminated between glucosylceramides with differences in the ceramide structure. These results suggest that antibody... 

Analysis of the glycosphingolipids in a mucosal scraping of human small intestine showed a peculiar distribution pattern. Glycolipids with one monosaccharide group (D-galactosyl- and D-glucosyl-ceramide) and those with more... 

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