Glycolide fiber properties

Effect of initiator type on copolvmer properties. Copolymer IV of p-dioxanone/glycolide at 90/10 weight composition was prepared using diethylene glycol (DEG) as the initiator. Fiber properties of the resulting copolymer were determined and compared with those of Copolymer II, which was made using 1-dodecanol as an initiator (as shown in Table IV). 

Typical Fiber Properties of Early Glycolide/Caprolactone Segmented Copolymers ... 

In-Vivo Absorption and breaking strength retention studies. For comparing PDS monofilament in-vivo properties with copolymeric fibers, a second 90/10 PDO/glycolide copolymer (II-A) was prepared and processed following similar schemes to those used for copolymer II. 

Polyglycolide was one of the first synthetic polymers used as a degradable surgical suture [122]. Fig. 8 shows the glycolide monomer and polymer structures. This aliphatic polyester is biodegradable and exhibits negligible toxicity when implanted in tissue. It is also possible to fabricate a strong fiber of this polyester with satisfactory mechanical properties. 

A number of polyesters made by two-stage end-grafting with trimethylene carbonate and glycolide were prepared and their respective properties are shown in Table 8.5. The data in Table 8.5 show that these polymeric high-melting materials, with a sufficiently high degree of crystallinity (measured in terms of AHf), are well-suited for use as fiber formers. 

Fu, B., Hsiao, B., Chen, G., Zhou J., Koyfman, I., Jamiolkowski D. D. and Dormier E., Structure and property studies of bioabsorbable poly(glycolide-co-lactide) fiber during processing and in vitro degradation. Polymer, 43,5527,2002. Fischer, E. W., Sterzel, H. J. and Wegner, G., Investigation of the structure of solution grown crystals of lactide copolymers by means of chemical reactions, Kolloid-Z. Z. Polym., 251,980. 1973. 

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