Glycogen spectral study

Normal human urine contains both squamous cells from the urethra and urothelial cells from the lining of the bladder. This former type may be further subdivided into glycogen-containing and glycogen-free squamous cells. In this study, we established that IR spectral methods, followed by multivariate data analysis, can distinguish these cell types. Acquisition of the urine-borne cells... 

The liver s role is to maintain chemical homeostasis and it can, in certain circumstances, be stressed by means of a metabolic load. One example has been to administer an oral fructose load which causes minimal spectral changes in normal subjects but, at very low dosage, results in an increase in the fructose-1-phosphate peak in patients with fructose intolerance. Other metabolic stresses have been administered to investigate galactose intolerance, glycogen storage diseases and cirrhosis. The rat liver (in situ or perfused) has been studied to elucidate details of carbohydrate and fatty acid metabolism, sometimes by a combination of and P NMR. The control of pH in the liver has also been studied. 

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