Glycine/glycolate

Since the vast majority of the substrates employed in diastereoselective syntheses are attached via a carboxyl function to the respective auxihary, this chapter deals with the diastereoselective a-fiinctionalization of chiral carboximides and esters, as well as with the homologation and aldolization alternatives of chiral glycinates, glycolates and haloacetates. Also discussed is the use of chiral a,/3-unsaturated representatives in the synthesis of e.p. linear /3- and a,/3-substituted carboxyhc acid derivatives and cyclic analogs (Diels-Alder reactions). Other methods, in which substrates are coupled, for example, via a carbonyl function in order to facilitate the diastereoselective a-aUcylation of aldehydes or... 

Partially dehydrated derivatives complexed with polyethylene glycol or propylene glycol exist. In the United of hydration has been replaced by glycine are particularly popular. Aluminum zirconium tetrachlorhydrex gly antiperspinant products. 

Liu et al. (2007) discovered that polyethylene glycol (PEG)ylated SWNTs are stable in vivo and demonstrate long blood circulation times and low uptake by the reticuloendothelial system. This group linked PEGylated SWNTs to an arginine-glycine-aspartic acid peptide, which was able to effectively target tumors in mice. 

---