Glycine collagen

Collagen Collagen is an extracellular structural protein 1052 amino acid residues. Collagen has an minsnal amino acid composidon it is about one-third glycine and is rich in proline. Note diat it also lacks Cys and Trp and is deficient in aromadc amino acid residues in general. 

These mechanisms for the synthesis of glycine present a partial barrier to the movement of FA carbons into this molecule, the most abimdant AA in collagen. On the other hand, proline is synthesized from a-keto glutarate which can be freely derived from either carbohydrates or FAs thus the synthesis of pro line does not present a barrier to entry ofFA-derived carbons into collagen. 

Bj = The 8-value of the j -th component of any set of body components. For example, hone collagen bone-apatite carbonate total body lipid, total body glycine muscle glycine etc. Each particular choice will have its own distinct equation. The set need not be complete— unlike D. 

Fig. 4. Helical structure of collagen, typical amino acid sequence within a collagen strand, and exchangeable versus non-exchangeable hydrogen atoms in an individual leucine molecule (Gly - glycine. Pro - Proline, Leu - leucine. Hyp - hydroxyproline.

Mechanism of NPYR Formation The consistent occurrence of NPYR in fried bacon and cooked-out fat has led to an intensive search for both the precursors and mechanism that could account for its formation. Although model system studies have implicated a number of compounds including proline, collagen, putreseine, spermidine, pyrrolidine and glycyl-L-glycine as possible... 

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