O-linked glycans

W-linked glycan O-linked glycans Glycosphingolipids (GSLs) Glycosoaminoglycans (GAGs)... 

Sialic acid-containing N-linked glycans O-linked glycans gly colipids... 

In addition, it should be noted that, inconveniently, the bond through which a glycan is attached to the peptide in a glycopeptide (whether N- or O-linked) is... 

The lack of a pan-specific or broad specificity O-glycanase makes chemical methods the most appropriate approach for the non-specific release of intact O-linked oligosaccharides from glycoproteins for site analysis.219 The most common chemical methods employed for the release of O-linked glycans are based on (3-elimination. The methods were originally developed to release the glycans for... 

Fig. 32. General mechanism for the alkaline P-elimination used for the release of a glycan from an O-linked glycopeptide.

M. V. Novotny, Y. Huang, and Y. Mechref, Microscale nonreductive release of O-linked glycans for subsequent analysis through MALDI mass spectrometry and capillary electrophoresis, Anal. Chem., 73 (2001) 6063-6069. 

A. M. Taylor, O. Holst, and J. Thomas-Oates, Mass spectrometric profiling of O-linked glycans released directly from glycoproteins in gels using in-gel reductive p-elimination, Proteomics, 6 (2006) 2936-2946. 

S. Schmitt, D. Glebe, K. Alving, T. K. Tolle, M. Linde, H. Geyer, D. Linder, J. Peter-Katalinic, W. H. Gerlich, and R. Geyer, Analysis of the pre-S2 N- and O-linked glycans of the M surface protein from human hepatitis B virus, J. Biol. Chem., 274 (1999) 11945-11957. 

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