Gluthathione-S-transferase

Mueller LA, Goodman CD, Silady RA, Walbot V. 2000. AN9, a petunia gluthathione S-transferase required for anthocyanin sequestration, is a flavonoid-binding protein. Plant Physiol 123 1561-1570. 

Habes, D., Morakchi, S., Aribi, N., Farine, J.-P, and Soltani, N., Boric acid toxicity to the German cockroach, Batella germanica Alterations in midgut structure, and acetylcholinesterase and gluthathione S-transferase activity, Pestic. Biochem. Physiol., 84,17, 2006. 

It is possible that dietary flavonoids participate in the regulation of cellular function independent of their antioxidant properties. Other non-antioxidant direct effects reported include inhibition of prooxidant enzymes (xanthine oxidase, NAD(P)H oxidase, lipoxygenases), induction of antioxidant enzymes (superoxide dismutase, gluthathione peroxidase, glutathione S-transferase), and inhibition of redox-sensitive transcription factors. 

Fig. 8. Terrapin bioprofiling pattern (adapted from ref. 47). Al, human gluthathione-5-transferase R8, rat glutathione-S-tranferase SI, schistosome glu-tathione-5-transferase HF2, housefly glutathione-i -transferase DAO, porcine D-amino acid oxidase BCh, equine butyryl cholinesterase Pap, papain PDE, snake venom phosphodiesterase I.

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