Glutathione modifier

Fang, C. and Zhon, Y. (2001). The electrochemical characteristics of Cgo-glutathione modified Au electrode and the electrocatalytic oxidation of NADH, Electroanalysis, 13, 949-54. 

Latus, A., J.-M. Noel, E. Volanschi, C. Lagrost, and P. Hapiot Scanning electrochemical microscopy studies of glutathione-modified surfaces. An erasable and sensitive-to-reactive oxygen species surface. Langmuir 27, 2011 11206-11211. 

FIGURE 31,14 (a) Schematic diagram of an FI system with the electrochemical detection of online generation of ABTS +. (b) Construction of a flow-through electrochemical detector, (c) FI signals obtained for water-soluble AOXs. The concentration of injected antioxidant solutions 250 pM for Tr, Asc, and uric acid 220 pM for reduced glutathione. (Modified from Milardovic, S., I. Kerekovic, and V. Rumenjak. 2007. Food Chem. 105 1688-1694.)... 

All selenium-containing proteins and enzymes in animals, microorganisms and plants incorporate selenocysteine non-specifically105 or as part of Se-dependent antioxidant enzymes such as glutathione peroxidase, (EC 1.11.1.9) which has a Se-cysteine residue in its active site.116 120 An active form of Se, selenophosphate, is produced by selenophosphate synthetase in several bacteria. This active form is required for the production of Secys-tRNA, a precursor for Se-cysteine.121 In a similar vein, a Se-containing modified-tRNA nucleoside, 5-methylaminomethyl-2-selenouridine, encodes a selenouridine synthase which replaces sulfur in tRNA with selenium.122... 

K. A. and Hollenberg, P.F. (2006) Identification of 17-alpha-ethynylestradiol-modified active site peptides and glutathione conjugates... 

The toxicity of isocyanates is the distant consequence of their reactivity as electrophiles toward alcohols, phenols, amines, and thiols [112]. These are, indeed, the mechanisms by which isocyanates react with and modify proteins and nucleic acids [113][114], Isocyanates also react reversibly with the tripeptide glutathione (GSH), the resulting conjugates being considered to be transport forms as well as products of detoxification [115] [116]. 

Lock EA, Ishmael J, Hook JB. 1984. Nephrotoxicity of hexachloro-1,3-butadiene in the mouse The effect of age, sex, strain, monooxygenase modifiers, and the role of glutathione. Toxicol AppI Pharmacol 72 484-494. 

Kardanov VZ, Petrosian EA, Pasechnikov VD et al. (2005) The estimation of efficiency of use of the haemosorbents modified with glutathion in treatment of an ischaemic syndrome -reperfusion extremities in experiment. Efferent Therapy 2 23-26... 

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