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Glutathione GSH-S-transferases

Lam, L. K. T., V. L. Spamins, and L. W. Wattenberg. Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione (GSH) S-transferase activity. Proc Am Ass Cancer Res 1982 23 88. [Pg.194]

Glutathione conjugation Glutathione GSH-S-transferase (cytosol, microsomes)... [Pg.17]

Glutathione conjugation Glutathione (GSH) GSH-S-transferase (cytosol, microsomes) Epoxides, arene oxides, nitro groups, hydroxylamines Acetaminophen, ethacrynic acid, bromobenzene... [Pg.85]

Considerable interest was generated when it was shown that substantial GSHPx activity exists in liver of selenium-depleted rats when LOOH is used as substrate but not H2O2 [20]. The enzyme was subsequently shown to be identical to a member of the glutathione-S-transferase family of enzymes [20,21,48], The enzyme was for a time called selenium-independent , or non-selenium dependent GSHPx and this nomenclature, which is confusing, has persisted in the literature. The role of GSH-S-transferases in the overall protection of cells against the harmful potential of LOOH has not been determined but it undoubtedly must form part of that protective mechanism. [Pg.127]

Dihydroxy-9,10-cpoxy-beny.pyrene, as well as other epoxide compounds, can be detoxified by glutathione. A number of different GSH S-transferases can catalyze the transfer of GSH to the epoxide. This transfer results in the formation of a GSH conjugate. An example of the reaction is shown in Figure 10.64. The resulting conjugate is not carcinogenic. It can be readily excreted in the bile. [Pg.834]

The glutathione (L-y-glutamyl-L-cysteinylglycine GSH) S-transferases (GSTs) are a multigene family of dimeric... [Pg.307]

Wahllander A, Soboll S, Sies H, Linke I, Muller M (1979) Hepatic mitochondrial and cytosolic glutathione content and the subcellular distribution of GSH S-transferases. FEBS Lett 97(l) 138-140... [Pg.106]

Almar, M.A., Diaz-Mayans, J., Romero, F.J., 1987. Glutathione content and GSH S-transferase activity in midgut gland of Procambarus clarkii. Sex differences, theeffect of fasting, and their implications in cadmium toxicity. Comp. Biochem. Physiol. 87C (2), 433 35. [Pg.451]

Figure 7-12. Use of glutathione S-transferase (GST) fusion proteins to purify recombinant proteins. (GSH, glutathione.)... Figure 7-12. Use of glutathione S-transferase (GST) fusion proteins to purify recombinant proteins. (GSH, glutathione.)...
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See also in sourсe #XX -- [ Pg.291 ]



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Glutathione GSH

Glutathione transferases

Glutathione-S-transferases

S-Transferase

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