Glutamate release from synaptosomes

Lynch M. A. and Voss K. L. (1990). Arachidonic acid increases inositol phospholipid metabolism and glutamate release in synaptosomes prepared from hippocampal tissue. J. Neurochem. 55 215-221. 

Bannister RA, Melliti K, Adams BA (2004) Differential modulation of CaV2.3 Ca2+ channels by Galphaq/11-coupled muscarinic receptors. Mol Pharmacol 65 381-8 Barclay JW, Craig TJ, Fisher RJ et al (2003) Phosphorylation of Muncl8 by protein kinase C regulates the kinetics of exocytosis. J Biol Chem 278 10538—45 Barrie AP, Nicholls DG, Sanchez-Prieto J et al (1991) An ion channel locus for the protein kinase C potentiation of transmitter glutamate release from guinea pig cerebrocortical synaptosomes. J Neurochem 57 1398-1404... 

Li X, Clark JD (2003) Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain. J Pain 4 101-107 Li X, Eisenach JC (2001) Alpha2A-adrenoceptor stimulation reduces capsaicin-induced glutamate release from spinal cord synaptosomes. J Pharmacol Exp Ther 299 939-944 Li X, Eisenach JC (2002) Nicotinic acetylcholine receptor regulation of spinal norepinephrine release. Anesthesiology 96 1450-1456... 

McMahon HT, Foran P, Dolly JO et at. (1992) Tetanus toxin and botulinum toxins type A and B inhibit glutamate, y-aminobutyric acid, aspartate, and met-enkephalin release from synaptosomes. J. Biol. Chem. 276 21338-21343. 

Wang S-J (2003) Cannabinoid CBi receptor-mediated inhibition of glutamate release from rat hippocampal synaptosomes. Eur J Pharmacol 469 47-55... 

Lingamanemi R, Hemmings HC Jr. Effects of anticonvulsants on veratridine- and KCI-evoked glutamate release from rat cortical synaptosomes. Neurosci Lett 1999 276 127-130. 

Vazquez E, Herrero I, Miras-Portugal MT, Sanchez-Prieto J. 1994. Role of arachidonic acid in the facilitation of glutamate release from rat cerebrocortical synaptosomes independent of metabotropic glutamate receptor responses. Neurosci Lett 174 9-13. 

Kainate receptors mediate a depression of evoked excitatory synaptic transmission in areas CA1 (40,88-90) and CA3 (35,37,91,92) of the hippocampus. There is strong evidence that in area CA1 the locus of this effect is presynaptic. Thus, activation of kainate receptors depresses release of L-glutamate from synaptosomes (88) and depresses both NMDA and AMPA receptor-mediated components of the evoked EPSC in parallel (88,90). Furthermore, the effects of kainate receptor activation on excitatory synaptic transmission in CA1 are associated with changes in presynaptic Ca2+ (89), an increase in paired-pulse facilitation (35,88,89), and a reduction in quantal content, as assessed using 1/CV2, but no change in mEPSC amplitude (90). 

Poii A, Lucchi R, Vibio M, Barnabei 0. (1991). Adenosine and glutamate modulate each other s release from rat hippocampal synaptosomes. J Neurochem. 57(1) 298-306. 

Reno LAC, Zago W, Markus RP (2004) Release of [3H]glutamate by stimulation of nicotinic acetylcholine receptors in rat cerebellar slices. Neuroscience 124 647 Reuben M, Clarke PBS (2000) Nicotine-evoked [3H]5-hydroxytryptamine release from rat striatal synaptosomes. Neuropharmacology 39 290... 

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