Glucose 6-phosphate gluconeogenesis, conversion

Now let us consider the further conversion of PEP and of the triose phosphates to glucose 1-phosphate, the key intermediate in biosynthesis of other sugars and polysaccharides. The conversion of PEP to glucose 1-P represents a reversal of part of the glycolysis sequence. It is convenient to discuss this along with gluconeogenesis, the reversal of the complete glycolysis sequence from lactic acid. This is an essential part of the Cori cycle (Section F) in our own bodies, and the same process may be used to convert pyruvate derived from deamination of alanine or serine (Chapter 24) into carbohydrates. 

When fructose-6-phosphate is generated by gluconeogenesis or photosynthesis (see chapter 15), an equimolar amount of glucose-1-phosphate is usually removed from the hexose monophosphate pool by conversion to storage polysaccharide (glycogen in animals and many kinds of microorganisms starch in green plants). 

Step 3 Conversion of Glucose-6-phosphate to Glucose (Reaction 2, p. 558) Stoichiometry and Energy Balance of Gluconeogenesis (Reaction 3, p. 558, Table 16.1) Substrates for Gluconeogenesis (Figure 16.4)... 

Gluconeogenesis in the liver and kidney often results in the release of glucose into the bloodstream, but under certain conditions it may lead to the production of glycogen. For this, glucose 1-phosphate is converted to UDPG, and then glycogen synthase catalyses its conversion to glycogen (see Section 3.5). 

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