Glucose conjugation

In insects, O-glucosides have been identified from some insecticide metabolism studies, including carbaryl, propoxur, carbofuran, DDT, and allethrin. 

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MAE in conjunction with high-performance liquid chromatography/mass spectrometry (HPLC/MS) shortened the cleanup procedure and provided satisfactory recoveries (97-102%) for the parent imazethapyr and its two metabolites (hydroxy and glucose conjugate metabolites). 

Plant In plants, dichlobenil is transformed into glucose conjugates, insoluble residues, and hydroxy products that are phytotoxic (Ashton and Monaco, 1991). These include three phytotoxic compounds, namely 2,6-dichlorobenzonitrile, 3-hydroxy-2,6-dichlorobenzonitrile, and 4-hydroxy-... 

Figure 7. Glucose conjugate of the major metabolite of chlorsulfuron...

Cycasin is a glucose conjugate of methylazoxymethanol. When hydrolyzed by the enzymes found in the gut, it releases methylazoxymethanol, which is carcinogenic. When the cycasin is given by other routes, i.p., for example, it is not hydrolyzed and so is not carcinogenic. 

Plants. At 62 dat, no residues were found major metabolites were the phenol formed by mono-demethylation, and its glucose conjugate... 

TABLE II. Phase I Reactions that Produce Metabolites Susceptible to Glucose Conjugation in Higher Plants... 

A direct relationship has been observed between the ability of some plant species to form 0-glucosldes of herbicides and resistance of those species to the herbicides however. In most cases a phase I reaction proceeds glucose conjugation and It Is not known whether the phase I reaction or conjugation results In herbicide detoxification. Chlorpropham is metabolized in plants by ring-hydroxylation and subsequent conjugation with glucose (Equation 3). In vitro, the... 

Malonate hemi-ester glucose conjugates of xenobiotics are one of the most common forms of complex glucoside conjugate produced In plants. They are formed by the action of malonyl CoA transferase on glucose conjugates In the presence of malonyl CoA as Indicated In Equation 14. At least 9 pesticides have been Isolated from 7... 

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