Glucose biosynthesis

One of the later steps in glucose biosynthesis is the isomerization of fructose 6-phosphate to glucose 6-phosphate. Propose a mechanism, using acid or base catalysis as needed. 

Figure 23.10 Mechanisms of type I and type II aldolase reactions in glucose biosynthesis.

Answer E. Hepatic fatty acid oxidation generates energy in the postabsorptive period when pyruvate is being converted to OAA for glucose biosynthesis. 

Figure 18.8 indicates that oxaloacetate may proceed in three directions toward glucose biosynthesis. It may be converted to phosphoenolpyruvate by a mitochondrial PEPCK, as shown in Equation (18.7) ... 

FIGURE 20.7 Carbon chains of the 20 common amino acids are converted into one of seven intermediates for further breakdown in the citric acid cycle. Ketogenic amino acids (red) can also enter the pathway for fatty-acid biosynthesis glucogenic amino acids (blue) can also enter the gluconeogenesis pathway for glucose biosynthesis. 

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