Gluconate degradation

The 2-keto-3-deoxy-6-phospho-D-gluconate (11) aldolase (KDPGlc aldolase or KdgA EC 4.1.2.14) provides the basis of the Entner-Doudoroff pathway that is used by many species of bacteria for the degradation of 6-phosphogluconate... 

Effect of Substitution (on the Glucon) on the Alkaline Degradation of Phenyl 0-v-Glucosides at 100°... 

The discovery that D-gluconic acid 6-phosphate may be degraded enzymatically to D-ribose 5-phosphate17,18 has thrown light on a possible path for the biogenesis of D-ribose. 

AN ORIGINAL BEHAVIOUR OF COPPER(II)-EXCHANGED Y FAUJASITE IN THE RUFF OXIDATIVE DEGRADATION OF CALCIUM GLUCONATE... 

The aim of this paper is to relate our attempts to perform heterogeneous catalysis of Ruff degradation of calcium D-gluconate to D-arabinose, using copper(II)-exchanged Y zeolite. Leaching of the transition metal is studied with the greatest care. From this study, a peculiar behaviour of the reactive system will be discovered. 

Copper(II)-exchanged Y Faujasite in the Ruff Oxidative Degradation of Calcium Gluconate... 

Copper(II)-exchanged faujasite was tested in the Ruff degradation of calcium gluconate and compared, under the same reaction conditions, with homogeneous catalysis by copper(II) sulphate. The amount of copper was the same in both cases and the reactions were stopped when hydrogen peroxide was totally consumed. D-arabinose and D-erythrose were the main products, glyceraldehyde was formed in small amount 2% yield). Blank experiment was carried out with the starting Na-faujasite, for the same reaction time as the one required for the oxidation in presence of copper zeolite. 

Table 1 Yield of arabinose and erythrose in the oxidative degradation of calcium gluconate by hydrogen peroxide catalysed by Cu(II)-exchanged faujasite. Comparison with homogeneous catalysis,...

For organisms where the predominant pathway is the Entner-Doudoroff pathway, fructose-1,6-bis-P is not a major metabolite in glucose degradation (because glucose-6-P is converted first into 6-P-gluconate and then to 2-keto,3-deoxy,6-P-gluconate) the activators for their ADPGlc PPase are fructose-6-P and pyruvate (Preiss, 1969, 1984 Preiss and Romeo, 1989). 

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