Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Gliomas treatment

In addition to their inherent self-sustaining properties, brain tumor stem cells may be more resistant to chemotherapy and radiation therapy than other tumor cells. Bao et al. (2006) found glioma stem cells (CD133+) were relatively radioresistant compared to CD133- tumor cells and preferentially activated the DNA damage checkpoint response. This relative resistance to standard treatment approaches of tumor stem cells compared to the majority of other cells within a tumor may underlie our current inability to cure patients with aggressive brain tumors such as glioblastoma. [Pg.257]

Ehtesham M, Kabos P, Kabosova A, Neuman T, Black KL, Yu JS (2002b) The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma. Cancer Res 62 5657-5663... [Pg.267]

Pollack IF, DaRosso RC, Robertson PL, Jakacki RL, Mirro JR, Blatt J, Nicholson S, Packer RJ, Allen JC, Cisneros A, Jordan VC (1997) A phase I study of high-dose tamoxifen for the treatment of refractory malignant gliomas of childhood. Clin Cancer Res 3 1109-1115... [Pg.113]

Fitzgerald DJ, Anderson JN (1999) Selective nucleosome disruption by drugs that bind in the minor groove of DNA. J Biol Chem 274(38) 27128-27138 Fox KR, Cons BM (1993) Interaction of mithramycin with DNA fragments complexed with nucleosome core particles comparison with distamycin and echinomycin. Biochemistry. 32(28) 7162—7171 Friedman HS, Kerby T, Calvert, H (2000) Temozolomide and treatment of malignant gliomas. CUn Cancer Res 6 2585-2597... [Pg.183]

Ronquist G, Hugosson R, Sjolander U, Ungerstedt U. 1992. Treatment of malignant glioma by a new therapeutic principle. Acta Neurochir (Wien) 114(1-2) 8-11. [Pg.253]

Several reasons have been cited for the limitations of the use of chemotherapy in the treatment of malignant glioma. Inherent and acquired drug resistance and the lack of good drug penetration through the blood-brain barrier have both been cited as obstacles. Sev-... [Pg.139]

Walker MD, Alexander E, Hunt WE, et al. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. J Neurosurg 1978 49 333-343. [Pg.142]

Walker MD, Green SB, ByarDP, etal. Randomized comparisons of radiotherapy and nitrosureas for the treatment of malignant glioma after surgery. N Engl J Med 1980 303 1323-1329. [Pg.142]

See other pages where Gliomas treatment is mentioned: [Pg.490]    [Pg.250]    [Pg.201]    [Pg.490]    [Pg.250]    [Pg.201]    [Pg.166]    [Pg.188]    [Pg.416]    [Pg.204]    [Pg.261]    [Pg.263]    [Pg.419]    [Pg.356]    [Pg.89]    [Pg.411]    [Pg.312]    [Pg.545]    [Pg.164]    [Pg.290]    [Pg.40]    [Pg.157]    [Pg.345]    [Pg.367]    [Pg.9]    [Pg.21]    [Pg.29]    [Pg.50]    [Pg.55]    [Pg.59]    [Pg.76]    [Pg.77]    [Pg.98]    [Pg.129]    [Pg.130]    [Pg.132]    [Pg.133]    [Pg.133]    [Pg.135]    [Pg.138]    [Pg.139]    [Pg.139]    [Pg.140]    [Pg.140]    [Pg.141]   
See also in sourсe #XX -- [ Pg.832 ]



SEARCH



Gliomas

Malignant glioma treatment

© 2024 chempedia.info