Glial cells Glutamate

Eliasof, S. and Jahr, C. E. (1996) Retinal glial cell glutamate transporter is coupled to an anionic conductance. Proc. Natl. Acad. Sci. USA 93,4153 4158. 

Bouvier, M., Szatkowski, M., Amato A., Attwell, D. (1992). The glial cell glutamate uptake carrier countertransports pH-changing anions. Nature 360 471-4. 

Figure 4.13 GABA release by reversed uptake ( retrotransport ). Depolarization of a neuronal, or glial cell process by glutamate, with a concomitant rise in [Na+]i reverses the operation of the GABA uptake carrier, raising [GABA]o. (Modified from Attwell, Barbour and Szatkowski 1993, with permission from the publisher Cell Press)...

Baslow MH (2000) Functions of W-acetyl-L-aspartatc and W-acetyl-L-asparty[glutamate in the vertebrate brain role in glial cell-specific signaling. J Neurochem 75 453—459... 

Alterations in neurotransmitter uptake and metabolism in glial cells / Modification in the ratio and function of inhibitory circuits / Local neurotransmitter imbalances (e.g., glutamate, y-aminobutyric acid [GABA]), acetylcholine, norepinephrine, and serotonin)... 

Brew, H. and Attwell, D. (1987) Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells. Nature 327,707-709. 

Barbour, B., Brew, H., and Attwell, D. (1988) Electrogenic glutamate uptake in glial cells is activated by intracellular potassium. Nature 335,433—435. 

Billups, B., Rossi, D and Attwell, D. (1996) Anion conductance behavior of the glutamate uptake carrier in salamander retinal glial cells../. Neurosci. 16, 6722-6731. 

Mort, D., Marcaggi, P Grant, J., and Attwell, D. (2001) Effect of acute exposure to ammonia on glutamate transport in glial cells isolated from the salamander retina../. Neurophysiol. 86, 836-844. 

Barbour, B Szatkowski, M., Ingledew, N., and Attwell, D. (1989) Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature 342,918-920. 

Spiridon, M., Kamm, D Billups, B., Mobbs, P, and Attwell, D. (1998) Modulation by zinc of the glutamate transporters in glial cells and cones isolated from the tiger salamander retina../. Physiol. (Lond). 506, 363-376. 

Figure 8.22 The glutamate/glutamine shuttle for provision of the glutamate neurotransmitter in the brain. This illustrates another role for glial cells in the brain.

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