Gliadin antibodies assays

In CD, autoantibody assays have generally replaced gliadin antibody assays. Measurement of gliadin antibodies is, however, advantageous in small children. Autoantibodies are often absent in CD children under 2 years of age [148, 149]. In another study, antibodies against tTG were found to develop not before an age of 1.3 years [150], Increased concentration of gliadin antibodies may be helpful in the investigation of other... 

The competitive ELISA format based on the R5 antibody offers additional special information when testing for samples containing prolamin fragments, such as beer, symp, or starches. These samples are in most cases below the LOQ of the sandwich assay but can be tested again with the competitive test kit to see whether smaller potentially toxic gliadin fragments are present. This limits the risk for celiac patients and allows industries to ensure the accuracy and use of the gluten-free statement. 

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