Gleditsia saponins

Gleditsia horrida Willd. G. sinensis Lam. G. xylocarpa Hance Zao Ci (Chinese honey locust) (leaf, fruit, seed) Saponin, arabinon, gleditsin, fisetin, fustin.50 Anthelmintic, febrifuge, treat cough, dysentery, flatulence, rectal prolapse, stroke, throat numbness, tetanus, emitic. 

From the fruits of Gleditsia japonica, which have been used in Japanese and Chinese folk medicine as a diuretic and expectorant, seven saponins (gleditsiasaponins B, C, Dj, D2, E, G and I) had been isolated. The structural elucidation of these saponins have been carried out by the chemical degradations, enzymatic hydrolysis and C-NMR spectra, and characterized as 3, 28-0-bisglycosides of echinocystic acid acylated with monoterpene carboxylic acid [46-49]. 

Konoshima, T. Yasuda, I. Kashiwada, Y. Corentino, C.M. Lee, K.H. Anti-AIDS Agents, 21. Triterpenoid Saponins as Anti-HIV Principles from Fruits of Gleditsia japonica and Gymnocladus chinensis and A Structure Activity Correlation. J. Nat. Prod. 1995, 58, 1372-1375. 

Ara, Glc, Rha, Xyl Saponins caspicaosides (triterpene) Gleditsia caspica Desf. 319... 

ScHULTEN, H.-R., T. Komori, T. Kawasaki, T. Okuyama, and S. Shibata Confirmation of New, High-mass Saponins from Gleditsia Japonica by Field Desorption Mass Spectrometry. Planta Medica 46, 67 (1982). 

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