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Gilman reagents reaction with epoxides

The synthesis of carbohydrates can be particularly difficult because of the large number of chiral centers and OH functional groups present. Epoxides can be useful s)mthetic intermediates in carbohydrate syntheses. Draw the product of the following reactions of a Gilman reagent with each epoxide. [Pg.630]

Hahdes of transition metals react with methyllithium to give methyl compounds. This reaction is alternatively afforded by organocopper compounds hke hthiumdialkylcuprates which are also known as Gilman reagents. These reagents are widely used for nucleophilic substitutions of epoxides, alkyl hahdes and for conjugate additions to a,p-unsaturated carbonyl compounds by methyl anion. [Pg.183]


See other pages where Gilman reagents reaction with epoxides is mentioned: [Pg.216]    [Pg.115]    [Pg.223]    [Pg.655]    [Pg.115]    [Pg.67]    [Pg.618]    [Pg.927]   
See also in sourсe #XX -- [ Pg.3 , Pg.223 ]

See also in sourсe #XX -- [ Pg.223 ]

See also in sourсe #XX -- [ Pg.3 , Pg.223 ]




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Epoxidation reactions, with

Epoxidation reagents

Epoxide reaction

Epoxides reactions

Gilman

Gilman reaction

Gilman reagent reactions

Gilman reagents

Reaction with epoxides

Reactions epoxidation

With epoxides

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