Gilbert studies

The hyperfine information for the series of azine radical donors requires deeper consideration. Gilbert et al. report detailed hyperfine information for unmethylated azine donors.However, the methylated donors provide a better model for application to the DCA species under consideration. Also, the Gilbert studies do not conclusively explain the experimental EPR data, noting a trend of reduced EPR resolution with donor heteroatom size, without conclusive explanation. We therefore have conducted a detailed study of the cw EPR for the oxidized methyl azine radical cation series (MePOZ , MePTZ" " , and MePSeZ ). 

The results from the CADe observer studies are equivocal. The early studies showed a definite advantage in using CADe, but the more recent and clinically realistic studies have been less clear. The studies by Taylor et al. showed no net benefit from using CADe, while the Gilbert study showed a 25% increase in sensitivity, but a 32% increase in the recall rate. As we shall see in the next section, the clinical evaluations of CADe presented a clearer picture. 

J.L. Baxeires, Y.S. Yow, and H. Gilbert, Study of the fluidized bed drying of various food products, Lebensm-Wiss. U.-Technol., 16 27 (1983). 

The central nervous system is a major target of endosulfan-induced toxicity in both humans and animals (Blanco-Coronado et al. 1992 Boyd and Dobos 1969 Boyd et al. 1970 Garg et al. 1980 Kiran and Varma 1988 Terziev et al. 1974). Therefore, individuals with seizure disorders, such as epilepsy, may be particularly susceptible because exposure to endosulfan may reduce the threshold for tremors, seizures, and other forms of neurotoxicity, as demonstrated in studies in rats (Gilbert and Mack 1995 Gilbert 1992). 

The beginning of the twentieth century also marked a continuation of studies of the structure and properties of electrolyte solution and of the electrode-electrolyte interface. In 1907, Gilbert Newton Lewis (1875-1946) introduced the notion of thermodynamic activity, which proved to be extremally valuable for the description of properties of solutions of strong electrolytes. In 1923, Peter Debye (1884-1966 Nobel prize, 1936) and Erich Hiickel (1896-1981) developed their theory of strong electrolyte solutions, which for the first time allowed calculation of a hitherto purely empiric parameter—the mean activity coefficients of ions in solutions. 

Petersen GR, Gilbert ES, Buchanan JA, et al. 1990. A case-cohort study of lung cancer, ionizing radiation, and tobacco smoking among males at the Hanford site. Health Phys 58(1) 3-11. 

RP Chan, DJ Pope, AP Gilbert, PJ Sacra, JH Buron, JE Lennard-Jones. Studies of two novel sulfasalazine analogs, ipsalazide and balsalazide. Digest Dis Sci 28 609-716, 1983. 

Ferguson and Bowman 1990 Gilbert and Rice 1987 Hopper et al. 1986 Krasovskii et al. 1979 Levin et al. 1988 Massaro and Massaro 1987 Overmann 1977 Rice 1985a). It appears that animals are affected at roughly the same blood lead levels as humans. Measured neurotoxic effects in animals include significantly delayed motor function and reflexes, decreased performance on learning tasks, and impaired spatial discrimination. Additional animal studies are needed to investigate the neurotoxic effects of subchronic inhalation exposures to establish external dose-effect relationships. 

However, nicotine also has been shown to stimulate the hypothalamic-pituitary-adrenal axis in rodents, leading to elevated plasma levels of adrenocorticotropic hormone and corticosterone (Andersson et al. 1983 Cam et al. 1979), which are known to exert a wake-promoting effect. However, studies in humans have shown that only intense smoking is able to activate the hypothalamic-pituitary-adrenal axis (Gilbert et al. 1992 Kirschbaum et al. 1992). Nicotine patches, in addition to their use in nicotine suppression and craving, have been used to explore the relationship between sleep and nicotine in human... 

Sequencing of parasite genes provides a powerful tool for the accurate identification of parasites and for systematic studies (Johnson and Baver-stock, 1989 Reddy, 1995 McManus and Bowles, 1996), and is based on either of the two original protocols (Sanger et al., 1977 Maxam and Gilbert, 1980). Cycle-sequencing (Murray, 1989), a PCR-based modification of the... 

Klemperer10 and Gilbert and Shapiro11 follow a similar line. The application of the concept of scope patents in the biotechnology sector is studied by Lemer.12 According to his estimate, broad patents are more valuable when there are multiple substitutes, which confirms theoretical findings. 

Owens D, Evans L. Population studies on Gilbert s syndrome. J Med Genet 1975 12 152-156. 

Zakharian, T.Y., Seryshev, A., Sitharaman, B., Gilbert, B.E., Knight, V., and Wilson, L.J. (2005) A fullerene-paclitaxel chemotherapeutic synthesis, characterization, and study of biological activity in tissue culture./. Am. Chem. Soc. 127, 12508-12509. 

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