Hyperplasia giant lymph node

Castleman disease (giant lymph node hyperplasia) can show structures that resemble follicles and intervening sheets of plasma cells, but the disease is usually restricted to lymph nodes, including the peribronchial nodes, while NLH is extranodal. Of interest, there have been cases of multinodular and diffuse LIP-like lesions (25,80) in the lung in the setting of the plasma cell variant of Castleman disease. 

V. Giant Lymph Node Hyperplasia (Castleman Disease)... 

Giant lymph node hyperplasia or Castleman disease is a lymphoproliferative disorder associated with prominent lymphadenopathy. Castleman disease can be localized or multicentric (95). Microscopically, there are hyaline vascular or plasma cell subtypes. 

Awotedu AA, Otulana BA, Ukoli CO. Giant lymph node hyperplasia of the lung (Castleman s disease) associated with recurrent pleural effusion. Thorax 1990 45(10) 775-776. 

---