GFAP

Harry GJ, Schmitt TJ, Gong Z, et al. 1996. Lead-induced alterations of glial fibrillary acidic protein (GFAP) in the developing rat brain. Toxicol Appl Pharmacol 139 84-93. 

These investigators found no effect of MDMA on GFAP expression, at doses that significantly depleted 5-HT levels in brain tissue. 

Bell PB Jr., Rundquist I, Svensson I, et al. Formaldehyde sensitivity of a GFAP epitope, removed by extraction of the cytoskeleton with high salt. J. Histochem. Cytochem. 1987 35 1375-1380. 

DHA docosahexaenoic acid GFAP glial fibrillary acidic protein... 

The five intermediate filaments and their respective tissues are listed in Table 3. Only the intermediate filament, cytokeratin, is selected as useful in the initial classification of tumors. The other intermediate filaments can cause diagnostic confusion because (1) they are usually not expressed in their poorly differentiated counterparts (especially GFAP, NFP, and Desmin) and (2) they are often coexpressed on many types of tumors. Poorly differentiated neuroectodermal tumors may often express more than two intermediate filaments. Vimentin demonstrates the most lineage infidelity. 

The components of the intermediate filaments belong to five related protein families. They are specific for particular cell types. Typical representatives include the cytokeratins, desmin, vimentin, glial fibrillary acidic protein (GFAP), and neurofilament. These proteins all have a rod-shaped basic structure in the center, which is known as a superhelix ( coiled coil see keratin, p. 70). The dimers are arranged in an antiparallel fashion to form tet-ramers. A staggered head-to-head arrangement produces protofilaments. Eight protofilaments ultimately form an intermediary filament. 

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