Genomic libraries eukaryotic

Figure 6.18. Creation of a Genomic Library. A genomic library can be created from a digest of a whole eukaryotic...

Before we study how genomic libraries are made we first need to understand the differences between the genetic organization in eukaryotic and prokaryotic cells. Bacterial genes are uninterrupted sequences of... 

DNA (section 2.4.1) than eukaryotic RNA (section 2.4.2). The result will be the construction of a collection of cloned DNA fragments propagated in bacteria that is called the genomic library. This library should contain representatives of every sequence in the chromosome of a prokaryotic cell and every expressed gene in the case of a eukaryotic cell. The final step consists of the screening of every recombinant clone to identify the required gene(s). 

The possibility of customization is the principal scientific advantage of the system. The microarray design, layout, and format are specific for each scientist s needs and objectives. The Design-on-Demand service offer by CombiMatrix try to cover this versatility. The researcher, though would define his experimental strategy with CombiMatrix support. Available libraries include eukaryotic, microbial, and viral genomes. Direct customer services are also offered. 

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