Genome trypanosomes

Robinson, D. R. and Gull, K. (1991) Basal body movements as a mechanism for mitochondrial genome segregation in the trypanosome cell cycle. Nature 352 731-733. 

In conclusion, the compositional patterns of the Trypanosome genomes indicate that compartmentalization is a phylogenetically very widespread situation in eukaryotes, as already predicted (Bernardi et al., 1985b). 

Indeed, genome compartmentalization was not only found in warm-blooded, and to a smaller extent, in cold-blooded vertebrates, but also in other eukaryotes, ranging from trypanosomes to Drosophila. At least in some cases, this compartmentalization seemed also to be linked to the thermodynamic stability of DNA. 

Musto H., Rodriguez-Maseda H., Bernard G. (1994). The nuclear genomes of African and American trypanosomes are strikingly different. Gene 141 63-69. 

Berriamn M, Ghedin E, Hertz-Fowler C, et al. The genome of the African trypanosome Trypanosoma brucei. Science 2005 309 416-422. 

Maxicircles, the trypanosomal equivalent of mitochondrial genomes in other eukaryotic cells, are approximately idendcal in size within a given species, but vary in size (19-39 kb) in different ttypanosomatids. They consist of a conserved coding r on and a nonttanscribed... 

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