Genome description

Human embryonic kidney cells, 21 Human genome, 2 Hydrogen bonding, 10 Hypothesis testing definition of, 239 description of, 227, 233 dose-response curves for, 239-243 F-test, 242t... 

Structural genomics is the systematic effort to gain a complete structural description of a defined set of molecules, ultimately for an organism s entire proteome. Structural genomics projects apply X-ray crystallography and NMR spectroscopy in a high-throughput manner. 

A phylogenetic profile is a description of the presence or absence of a particular protein in a set of organisms whose genome has been sequenced. The profile is a string with n entries, each one bit, where n is the number of... 

In CGP, the genome corresponding to a graph is an expansive description of (1) each node in the graph and (2) how it connects to other nodes. An example of such representation follows. 

This definition does not identify one special structure it is a descriptive term for a variety of minimal cells. Although there is no consensus on this definition, scientists do agree on the main points. Thus, a minimal genome should have 200-300 genes. The question arises as to whether it is conceivable that this number can be further reduced, or whether we need to devise other, as yet unknown, precursor systems. 

The ultimate goal of structural genomics is to provide a complete three-dimensional description of any gene product. Also, as the structures of more and more proteins of known function are elucidated, it should become increasingly possible to link specific functional attributes to specific structural attributes. As such, it may prove ultimately feasible to predict protein function if its structure is known, and vice versa. 

Applicable to large genome-scale systems Description includes regulatory properties... 

S. Nicolay, E.-B. Brodie of Brodie, M. Touchon, Y. d Aubenton-Carafa, C. Thermes, and A. Arneodo, Erom scale invariance to deterministic chaos in DNA sequences towards a deterministic description of gene organization in the human genome. Physica A 342,270-280 (2004). 

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