Genetic factors, dilated cardiomyopathy

Charron, P., Tesson, E., Poirier, O., et al. (1999) Identification of a genetic risk factor for idiopathic dilated cardiomyopathy. Involvement of a polymorphism in the endothehn receptor type A gene. CARDIGENE group. Eur. Heart J. 20, 1587-1591. 

To date, proteomic investigations into human heart disease have centered on dilated cardiomyopathy (DCM). DCM is a disease of unknown etiology, characterized by impaired systolic function resulting in heart failure. Known contributory factors of DCM are viral infections, cardiac-specific autoantibodies, toxic agents, genetic factors, and sustained alcohol abuse. As many as 100 cardiac proteins... 

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