Genes promoter region

Fig. 9.2 Representative examples of the methylation-specific polymerase chain reaction (MSP) analyses for gene promoter regions. Lanes Lf and M indicate the presence of unmethylated and methylated template, respectively. Placental DNA (PDNA) and in vitro methylated DNA (IMD) served as negative and positive controls, respectively. Water (H) was used to detect contamination. Samples 1, 3, 4, and 7 indicate the presence of a methylated promoter DNA with various degrees of methylation, and samples 2, 5, and 6 represent an unmethylated promoter...

Timmermann B, Li GH, Luft FC, Lund-Johansen P, Skrabal F, Hoehe MR. (1998) Novel DNA sequence differences in the beta2-adrenergic receptor gene promoter region. Hum Mutat. 11, 343-344. 

Smith JD, Brinton EA, Breslow JL. Polymorphism in the human apolipoprotein A-I gene promoter region. Association of the minor allele with decreased production rate in vivo and promoter activity in vitro. J Clin Invest. 1992, 89 1796-1800. 

Association between the G1001C polymorphism in the GRIN1 gene promoter region and schizophrenia. Biol Psychiatry 53 617-619. 

Saito T, Guan F, Papolos DF, Rajouria N, Fann C, et al. 2001. Polymorphism in SNAP29 gene promoter region associated with schizophrenia. Mol Psychiatry 6 ... 

Wonodi I, Hong LE, Avila MT, Buchanan RW, Carpenter WT Jr, et al. 2005. Association between polymorphism of the SNAP29 gene promoter region and schizophrenia. Schizophr Res 78 339-341. 

Suzuki A, Kondo T, Mihara K, et al. The -141C Ins/Del polymorphism in the dopamine D2 receptor gene promoter region is associated with anxiolytic and antidepressive effects during treatment with dopamine antagonists in schizophrenic patients. Pharmacogenetics 2001 ll(6) 545 50. 

Fig. 6. 33. Plasmid DNA constructed for gene delivery contains a therapeutic gene sequence, eukaryotic gene promoter regions, prokaryotic origins of replication, selectable markers, as well as RNA processing sequences and other plasmid-derived sequences. (Adapted from Ledley FD. Pharmaceutical approach to somatic gene therapy. Pharm Res 1996 13 1595-1614 with permission.)...

Rusiecki, J.A., Byrne, C., Gaidzicki, Z., et al., 2013. PTSD and DNA methyla-tion in select immune function gene promoter regions a repeated measures case-control study of US Military service members. Front. Psychiatry 4,56. 

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