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Genes and medicine

Mutations associated with inheritable diseases are numbered in MIM notation as described in McKusick, V. A. Mendelian Inheritance in Man. A Catalog of Human Genes and Genetic Disorders, 12th edn. Baltimore Johns Hopkins University Press, 1998. An updated Internet version is found at Online Mendelian Inheritance in Man, OMIM . McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information, National Library of Medicine (Bethesda, MD), 2000, www.ncbi.nlm.nih.gov/ omim/. [Pg.719]

The work of the Human Genome Project has allowed researchers to begin to understand the blueprint for building a person. As researchers learn more about the functions of genes and proteins, this knowledge will have a major impact in the fields of medicine, biotechnology,... [Pg.47]

Rous, Peyton (1911) A sarcoma of the fowl transmissible by an agent separable from the tumor cells. Journal of Experimental Medicine. 13,397-411. Varmus, H. and Weinburg R. A. (1993) Genes and the Biology of Cancer. [Pg.322]

Siest, G., Pillot, T., Regis-Baftly, A., Leininger-MuUer, B., et al. (1995) Apolipoprotein E an important gene and protein to foUow in laboratory medicine. Clin. Chem., 41, 1060-1086. [Pg.348]

Kumagai, K., Hiyama, K., Oyama, T., Maeda, H., and Kohno, N. (2003) Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis. International Journal of Molecular Medicine. 11, 593-600. [Pg.433]

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