Generation and Reaction of Aryllithium Species Bearing Ketone Carbonyl Groups

4 Generation and Reaction of Aryllithium Species Bearing Ketone Carbonyl Groups 

To examine how the residence time affects the results, the following experiment was carried out. Mesityllithium prepared by the reaction of mesityl bromide with -BuLi using a flow microreactor system was reacted with the o-iodophenyl butyl 

4 I-Li exchange reaction of o-iodophenyl butyl ketone with mesityllithium followed by protonation 

Anastas, J.C. Warner, Green Chemistry Theory and Practice (Oxford University Press, New York, 1998) 

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