Gastroesophageal reflux disease GERD

Gastrin Releasing Peptide Gastroesophageal Reflux Disease (GERD)... 

Explain the underlying causes of gastroesophageal reflux disease (GERD). 

The blood pressure of a 65-year-old male is well controlled by a Ca2+" channel blocker that is used to treat his essential hypertension. When placed on cimetidine to control symptoms related to gastroesophageal reflux disease (GERD), he has episodes of dizziness. I low does cimetidine s effect on Ca2+ channel blockers account for the dizziness ... 

Proton pump inhibitors (PPIs), such as omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole, are commonly prescribed to treat symptoms of heartburn, acid reflux, chest pain, dyspepsia, and chronic cough. PPIs inhibit the transfer of protons into the stomach lumen. Pharmacological acid suppression is thus used to treat gastroesophageal reflux disease (GERD) and esophagitis, peptic ulcers, and Helicobacter pylori infection as well as to prevent ulcer development with concurrent nonsteroidal anti-inflammatory drug use. 

Mosapride is a benzamide, structurally close to cisapride. This 5-HT4 receptor agonist, which is also a 5-HT3 and D antagonist, was launched for the treatment of gastroesophageal reflux disease (GERD) (Figure 8.71). 

IV form is indicated for short-term treatment (7 to 10 days) of gastroesophageal reflux disease (GERD), as an alternative to oral therapy in patients who are unable to continue taking the oral form. Safety and efficacy of injectable form as an initial treatment for GERD have not been demonstrated. 

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