Gastrin level

Acid rebound Antacids may cause dose-related rebound hyperacidity because they may increase gastric secretion or serum gastrin levels. 

CN171 Frank-Peterside, N. The effect of different dietary fats on gastrin levels in the pyloric antrum and plasma of weaner and adult Wistar rats. Afr J Med Med Sci 2000 29(2) 135-139. 

Figure 1. Conscious cat with gastric fistula. Effect of (R)a-methylhistamine (MHA, pmol/kg i.v.) on acid secretion and plasma gastrin levels stimulated by 2-deoxy-D-glucose (100 mg/kg i.v.) (Co). On the ordinate percent responses in comparison with maximum responses considered arbitrarily as 100. Mean values SEM from 5 cats. P <0.05 and 73<0 01 vs control values.

Chang M, Tybring G, Dahl ML, et al. Interphenotype differences in disposition and effect on gastrin levels of omeprazole—suitability of omeprazole as a probe for CYP2C19. Br J Clin Pharmacol 1995 39 511 518. 

Effect of Candidate Compounds with Antisecretory Potential on Serum Gastrin Levels... 

Serum gastrin levels are determined as pg/ml. Statistical differences (p < 0.05) are calculated using appropriate statistical methods. 

Zollinger-Ellison syndrome A rare disorder where there is excessive gastric acid secretion due to high gastrin levels in the blood produced by an enlarged pancreas or pancreatic tumour. 

Berger AC, Gibril F, Venzon DJ, Doppman JL, Norton JA> Bartlett DL, et al. Prognostic value of initial fasting serum gastrin levels in patients with ZoUinger-Ellison syndrome. J Clin Oncol 2001 19 3051-7. 

Gastrin — Gastrin may possibly be important in other disease states. Elevation of serum gastrin levels have been reported in rheumatoid arthritis patients and elevated gastrin levels have been hypothesized to contribute towards maturity onset diabetes. ... 

Other potentially useful tests include antibody testing and serum gastrin levels. Positive anti-intrinsic factor antibodies may be present in approximately half of patients with pernicious anemia, but is highly specific for the disease. Additionally, an estimated 85% of patients have anti-parietal cell antibodies, but they are nonspecific, as 3% to 10% of healthy patients have these antibodies. Fasting serum gastrin levels are elevated in more than 70% of patients with cobalamin deficiency and may be useful in assessing patients with borderline... 

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