Gastric cancer pathology

FIGURE 10.2 Proposed sequence of pathologic events in gastric cancer. 

The pathologic specimens of the stomach and tumor (resected in 1881 by Billroth) of Theresa Heller, on display at the Josephinum in Vienna. The left bottle is the resection specimen, containing the obstructed pyloric antrum that was successfully resected. The right specimen is of the stomach, recovered at autopsy SVi months later, when the patient died of hepatic metastases. The patent gastroduodenal anastomosis is evident. It is worthy of note that more than a century later, the survival of patients with gastric cancer has not improved appreciably since the first intervention by Billroth. 

To assist in the interpretation of data to follow, a brief note on the sequence of pathological events preceeding gastric cancer is included. It is currently believed that certain lesions of the stomach, often designated as pre-cancerous lesions are associated with an increased predisposition to... 

Doria MI Jr, Doria LK, Faintuch J, Levin B. Gastric mucosal injury after hepatic arterial infusion chemotherapy with floxuridine. A chnical and pathologic study. Cancer 1994 73(8) 2042-7. 

Hiccup is a forceful, involuntary inspiration commonly experienced by fetuses, children, and adults. Its purpose is unknown, and its pathophysiology still poorly understood. Short hiccup bouts are mostly associated with gastric distention or alcohol intake. They resolve spontaneously or with simple folk remedies and do not require medical attention. In contrast, prolonged hiccup is a rare but disabling condition that can induce depression, weight loss, and sleep deprivation. A wide variety of pathological conditions can cause chronic hiccup myocardial infarction, brain tumor, renal failure, prostate cancer, and abdominal surgery are only a few of these conditions. 

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