Galactose-binding

The disaccharide derivatives 196 and 197 of N-tosyl-L-serine, of interest for the study of D-galactose-binding lectins, were prepared by Kaifu and Osawa148 from 194 and 195, respectively, by protection of 0-4 and -6 with a benzylidene group, condensation of the acetal with tetra-O-acetyl-a-D-galactopyranosyl bromide (110) under Koenigs-Knorr conditions, and deprotection. 

More elaborate methods of blocking or eliminating the B-chain galactose binding site also can be done to prevent nonspecific cytotoxicity. For instance, the crosslinking agent may have a... 

CIBl = Calcium- and integrin-binding protein DGBP = D-Galactose binding protein Pmrl = plasma membrane ATP-ase related protein. 

D-Galactose binding protein 7 2 aspartates 1 glutamate (bidentate) 1 asparagine 2 glutamine (369)... 

D-galactose- but not a-D-mannose- or BSA-functionalized nanotubes, indicating that the multivalent interactions between the nanotube-bound galactoses and the E. coli cell surface galactose-binding proteins probably dictate the Gal-SWNT-... 

Fig. (24). Reaction of guar (Gu), and a-galactose-BSA(a) and p-galactose-BSA (p) with anti-guar antibodies (A), anti P-Galactose Abs (B) and anti a-galactose binding lectin (C).

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