Gadolinium complexes kinetic inertness

Following some detailed studies of kinetically inert complexes of yttrium - for targeted radiotherapy - and of gadolinium, for use as contrast agents in magnetic resonance imaging, we were attracted by the chemical versatility of single component, luminescent lanthanide complexes. The monoanionic tetracarboxylate and... 

Metallotexaphyrins are typically rather soluble in polar media. In fact, complexes such as the all-alkyl systems 9.70-9.72 show significant solubility (to ca. 10 M concentrations) in 1 1 (v/v) methanol/water mixtures. Perhaps more importantly, metallotexaphyrins have been demonstrated to be rather hydrolytically inert. For instance, detailed kinetic studies carried out on a solution of gadolinium(III) texaphyrin 9.70 in a 1 1 methanol/water mixture revealed that the half-life for... 

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