Further Rare Anomalies of Lipid Metabolism

A number of diseases apparently due to anomalies in lipid metabolism has been seen in only a few cases or even in single families. Affected sibs here frequently point to autosomal recessive inheritance, but the small number of observations does not permit a definite statement. 

Here the syndrome of familial hypolipidemia observed in two sisters by Hooft et al. (1962) has to be mentioned, which is characterized by extreme low concentrations of all plasma lipid fractions, retarded development, atypical retinitis pigmentosa, erythemato-squamous skin lesions and aminoaciduria. 

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