Furosemide hyperuricemia with

The most important side effects of the thiazide diuretics, chlorthalidone, furosemide, ethacrynic acid and metolazone are potassium losses with resultant hypokalemia, and hyperuricemia. Hyperuricemia may result in acute attacks of gouty arthritis in individuals with a gouty diathesis. 

Correct answer = D. Among black patients, diuretic and calcium channel blockers are more effective than ACE inhibitors or p-blockers. Diuretics are effective among the elderly. Thiazide diuretics cause hyperuricemia and can precipitate a gout attack in susceptible individuals. Thiazide diuretics increase LDL cholesterol and may increase the risk of atherosclerosis in patients with hyperlipidemia. Patients with evidence of elevated catecholamines are best treated with p-blockers. Thiazides cannot promote sodium excretion when renal function is severely impaired. The loop diuretics, such as furosemide, are used in patients with impaired renal function. 

Furosemide metabolic alkalosis hyperuricemia blood dyscrasias rashes lipid changes as with thiazide-type diuretics... 

Furosemide (Lasix) Inhibits chloride reabsorption in thick ascending loop of Henie. High loss of K+ in urine. Preferred diuretic in patients with low GFR and in hypertensive emergencies. Also, edema, pulmonary edema, and to mobilize large volumes of fluid. Sometimes used to reduce serum potassium levels. Hyponatremia, hypokalemia, dehydration, hypotension, hyperglycemia, hyperuricemia, hypocalcemia, ototoxicity, sulfonamide allergy, hypomagnesemia, hypochloremic alkalosis, hypovolemia. 

A 65-year-old man with a history of bilateral ureterohydronephrosis with chronic renal insufficiency, hyperuricemia, and bladder carcinoma reported a 2-month history of prurigi-nous lesions on his trunk and limbs. His medications included long-term allopurinol and calcium, and furosemide (dose not stated), which he had taken for 4 months. The diagnosis was confirmed on skin biopsy. One year after stopping furosemide, his lesions were still present but had become less symptomatic. 

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