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Fundamentals of Quadruplex Structures

Polymers other than canonical DNA and RNA oligonucleotides can also form G-quadruplexes. The ability to alter the polymer backbone may result in G-quadruplexes with a variety of potential applications in supramolecular chemistry, biotechnology, and nanotechnology. In addition, studies on nucleic acid analogs may lead to insights into the structural factors that control fundamental issues about the thermodynamics and kinetics of the G-quad-ruplex motif in the parent DNA and RNA nucleic acids. [Pg.288]

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Quadruplexes

Structural fundamentals

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