Functionalisation via Biotin End Group

Grande and E.L. Chaikof,/owmd / of the American Chemical Society, 2002,124, 7258. 2002, American Chemical Society [28] 

Another easy and efficient way to prepare glycopolymer bioconjugates is via click chemistry. However, this strategy generally includes several step reactions. One elegant approach was demonstrated by Shi and co-workers [30]. First, well-defined azide-functionalised polymers bearing pendant e -butyl acrylate moieties were prepared via ATRP in the presence of CuBr, PMDETA and 2-bromo-2-methylpropionic 

Ladmiral, E. Melia and D.M. Haddleton, European Polymer Journal, 2004,40,431. 

Hetzer, G. Chen, C. Barner-Kowollik and M.H. Stenzel, Macromolecular Bioscience, 2010,10,119. 

Slavin, J. Burns, D.M. Haddleton and C.R. Becer, European Polymer Journal, 2011, 47, 435. 

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